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Introduction The growth hormone (GH)-insulin-like growth factor I (IGF-I) axis plays a critical role in promoting linear growth in children ( Insulin, when secreted from pancreatic -cells, is transported by the portal vein directly to the liver resulting in high hepatocyte exposure

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However, according to research published in the journal Acta Biomaterialia , about 95% of GHK-Cu injected into the dermis is metabolized and excreted from the body