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Indeed, there are around 30 isoforms of RGS proteins that, when bound to G through their GAP domain, accelerate the hydrolysis rate to 30 times/sec

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Arch Biochem Biophys 342 :126133
10.3389/fvets.2021.703101 154 VarnerD

It contains the nitro (-NO 2 ) group, reduction takes place in this group and it is converted into the amino (-NH 2 ) group and the remaining structure is the same
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