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In severe cases, there may also be thrombocytopenia, severe leukopenia, or pancytopenia

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& Matsuda, S

also found that the autophagy kinase ULK1 can induce the autophagic degradation of mitochondria by phosphorylating the ser-73 and ser-254 residues of Sestrin 2 under copper-induced oxidative stress conditions (Kim et al., 2020)

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For example , falling over with a ski pole in your hand