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Ann Rheum Dis 74:14741478

A 50% reduction in tumor volume compared with free anti-CTLA-4 indicates the potential of peptide-based nanoparticles to improve the clinical standard [140, 141]
Additionally, in another Phase II study targeting patients with T2DM, orforglipron also showed significant effects in reducing A1C and weight, achieving the studys primary and secondary endpoints

J Am Chem Soc, 2014, 136: 53515358 Zhao M, Wang J, Lei Z, et al

The HSD17B1 and HSD17B3 encoded enzymes are involved in the synthesis of the male and female sex hormones
