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The biosynthesis of autophagosomes involves the appearance of a phagophore in the cytoplasm, which then expands, sequestering cytosomal components, before eventually sealing to form a spherical double-membraned vesicle called the autophagosome The newly-formed autophagosome then translocates to and fuses with the lysosome to form an autolysosome

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Patients should rotate injection sites to minimize skin irritation or injection site issues
