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Subsequently, a cascade of reactions ensues, which includes the interaction of superoxides with nitric oxide (NO) to yield peroxynitrite (ONOO ) and the conversion of H 2 O 2 into water, eventually leading to the generation of hydroxyl radicals ( A significant source of ROS emerges from the end substrate of the respiratory chain, situated within the inner mitochondrial membrane

AXL expression in pediatric AML is associated with putative LSC and correlates with a distinct set of proteins associated with cell metabolism, cell cycle, and unfolded protein response