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PTC exhibits high heterogeneity and is currently classified into four major molecular subtypes, including the immune-enriched subtype, BRAF -enriched subtype, stromal subtype, and copy number variation (CNV)-enriched subtype [2]

The analysis was performed on a C18 column (YMC-Pack Pro C18, 250 X 4.6, S-5 m, 12 nm) under reversed-phase partition chromatographic conditions

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One of the investigations reported that NPs were loaded with nuclear factor kappa B (NF-B) inhibitors, a key regulator of inflammation, which could suppress the microglial activation and decrease the production of pro-inflammatory cytokines