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Protein assay showed that Y-56 overexpression remarkably reduced the phosphorylation levels of AKT and ERK without changing the total AKT and ERK expression in PSCs, whereas Y-56 inhibition promoted p-AKT and p-ERK expression (Figures 8A,B

most published evidence is observational or comes from cell culture research

Conclusion Bidirectional kidney-liver crosstalk plays an important role in the well-being maintenance and pathogenesis of certain disorders

This review provides new insight into the classification of drug resistance mechanisms in ovarian cancer and may facilitate in the successful treatment of resistant ovarian cancer

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A.KrauseR.et al
