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B12 tested at last

Two unnatural amino acids (aminoisobutyric acid at positions 2 and 20, -methyl-leucine at position 13) confer protease resistance and allow the molecule to survive long enough in plasma for once-weekly dosing in clinical studies

Great as usual I was pleased with the delivery speedbut unhappy that the bottle and its contents were pretty warm upon arrival

As a medication, we applied BPC 157 (10 g/kg, 10 ng/kg), L-NAME (5 mg/kg), L-arginine (100 mg/kg) alone and/or combined, intravenously, immediately after intravenous heparin administration, while controls received simultaneously an equivolume of saline (0.5 ml/kg intravenously)

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