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The latter is an imbalance between the generation and elimination of ROS in favor of the former with various consequences for cell physiology (Lushchak, 2014b)

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doi: 10.1039/D2FO01577C 461 wirkoszGSzczygieALogoKWrzeniewskaMGomukaK
The mevalonate pathway affects the production of CoQ10, an endogenous antioxidant involved in regulating iron metabolism

Its discovery opened new avenues for understanding how mitochondria communicate with the rest of the cell to regulate systemic metabolism
In obese models, exposure was associated with reduced weight and fat mass, alongside suggested increases in receptor RNA expression
