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Semaglutide (marketed under brand names like Wegovy and Ozempic) and Tirzepatide (Mounjaro and Zepbound) are GLP-1 receptor agonists that help regulate appetite, insulin, and metabolism

The enrollment criteria for this trial required painful neuropathic symptoms of the extremities consistent with small fiber neuropathy

PLoS ONE 12:e0181748

There are no published human clinical trials of Dihexa, and therefore no human safety, toxicology, or pharmacokinetic data

It inhibits the release of pro-inflammatory factors in response to TLR4 stimulation and induces immune tolerance, a non-butyrate-dependent effect (99)

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