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This resistance is mediated by different causes and mechanisms, (that are resumed in Table 1 and excellently summarized in different review articles [78].One of the most obvious and intriguing mechanisms of resistance involves alteration in CD38 expression, a crucial factor in both primary and acquired resistance to anti-CD38 therapies

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doi: 10.1016/s1079-2104(98)90173-1 84 WuFWengSLiCSunJLiLGaoQ

[DOI] [PubMed] [Google Scholar] 162.Chung S.-Y., Moriyama T., Uezu E., Uezu K., Hirata R., Yohena N., Masuda Y., Kokubu Y., Yamamoto S