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Lpez-Benito S, Snchez-Snchez J, Brito V, Calvo L, Lisa S, Torres-Valle M, Palko ME, Vicente-Garca C et al (2018) Regulation of BDNF release by ARMS/Kidins220 through modulation of synaptotagmin-IV levels

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doi: 10.1016/j.jad.2013.01.014

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After overeating, Wnt/-catenin signal transduction in adipose tissue is inhibited, manifesting as increased expression of inhibitors of the canonical Wnt signalling pathway, such as SFRP2, FRZB/SFRP3, and DKK3, and increased phosphorylation and total GSK-3 levels

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Sermorelin therapy is indicated only for individuals with demonstrated need (such as GH deficiency)

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