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Patients with pernicious anaemia, malabsorption disorders (such as Crohn's disease or coeliac disease), or following gastric surgery require regular B12 supplementation to prevent serious complications including megaloblastic anaemia and neurological damage

The case for combining The mechanisms are genuinely complementary

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A 250 mcg target dose is 0.1 mL at this concentration

Often, the industry's conflict of interest is apparent rather than subtle since disease prevention, non-drug-dependent methods lack commercial interest, as healthy people have little-to-no dependency and are not lucrative clients for the medication industry (279)

Best practice: avoid repeated freezethaw cycles and limit exposure to heat and moisture