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The compound appears well-tolerated in animals at doses well above those producing metabolic effects

While human longevity data is still emerging, the mechanistic basis for anti-aging effects is well-established

However, if you are a vegetarian and vegan, you may be interested in trying out other sources of vitamin B12, such as nori, shitake mushroom, and fortified foods

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But for patients who have done the foundational work diet, movement, sleep, lab optimization and are still hitting a wall with fat metabolism or body composition, it may be a worthwhile piece of the puzzle