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Luteolin as an anti-inflammatory and neuroprotective agent: a brief review

[DOI] [PubMed] [Google Scholar] 159.Matias-Guiu J.A., Delgado-Alonso C., Dez-Cirarda M., Martnez-Petit ., Oliver-Mas S., Delgado-lvarez A., Cuevas C., Valles-Salgado M., Gil M.J., Yus M., Gmez-Ruiz N., Polidura C., Pagn J., Matas-Guiu J., Ayala J.L

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The BV and bilirubin (BR), produced by HO-1 as reducing agents, function as potent antioxidants and anti-inflammatory mediators, displaying cytoprotective properties against harmful stimuli in both in vivo and in vitro contexts

Regarding fibrosis/cirrhosis, exercise upregulates CCN1, which binds to TGF- and induces endoplasmic reticulum stress, thereby reducing HSCs