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The gut microbiota metabolite capsiate regulate SLC2A1 expression by targeting HIF-1alpha to inhibit knee osteoarthritis-induced ferroptosis

(Removed: "Medical") Pei Y, Liu H, Yang Y, et al

In addition to assessment methods such as the Roussel Uclaf Causality Assessment Method (RUCAM) ( in vitro prediction models with high accuracy are available, generalizing the characteristics of DILI in a single in vitro model and using it for screening and disease prediction is difficult due to the individual variability of DILI ( AI research, which takes advantage of big data and machine learning, is a relatively new method for diagnosing and predicting DILI, which can help identify new drugs under development with hepatotoxicity to reduce drug development costs in the early stage ( in vitro experiments ( In conclusion, DILI cannot be eliminated as an adverse drug reaction, and our ultimate goal is to minimize its impact on clinical outcomes, and patient health

Klein S, Gastaldelli A, Yki-Jrvinen H, Scherer PE

ROSs are crucial for the onset and progression of cerebrovascular diseases [194]

What is NAC (N-Acetyl Cysteine)
