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Similarly, tert-butyl hydroperoxide (t-BuOOH) increases lipid ROS production, inducing oxidative stress, mitochondrial depolarization, and DNA damage

It was validated that BIM is a FOXO1 target gene and is induced under the stimulation of cAMP

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10p), and GGsTop delivery in drinking water led to inhibition of GGT activity in animals and suppressed tumour growth (Extended Data Fig