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A phase 2b, randomized, placebo-controlled, double-blind, dose-ranging study of the neurokinin 3 receptor antagonist fezolinetant for vasomotor symptoms associated with menopause

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The CN-dependent route is further divided into early and late C-6 oxidation pathways

Hence, we showed that both liver models produce CCBL enzymes that have the ability to cleave the C-S bond of cysteine conjugates, which tends to demonstrate the involvement of the liver in the formation of these thiomethyl metabolites

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