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The net result of these actions is inhibition of C-fibre-evoked postsynaptic excitation, although TRPA1-mediated calcium influx may initially increase spontaneous excitatory postsynaptic currents via activation of ionotropic glutamate receptors (iGluR)

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Cortes J, Ravandi F, Garcia-Manero G, Kadia T, Borthakur G , Konopleva M, Daver N, Pemmaraju N, Jabbour E, Estrov Z, Phung T, Urity V, Uchida A, Paradela J, Andreeff M, Kantarjian H
