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Microglial NF-B activation under GSH-depleted conditions creates a pro-inflammatory loop where increased ROS promotes NF-B activation, which upregulates inflammatory cytokines and further stimulates oxidative stress (Liu et al., 2017

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Break TJ, Witter AR, Indramohan M, Mummert ME, Dory L, Berg RE

Dual antiplatelet treatment in the form of clopidogrel and aspirin prevents future ischemic events more effectively than aspirin alone but the dual treatment also increases the risk of hemorrhage [109]