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Taken together, these findings suggest that targeting the mitochondrial electron transport chain, specifically complex II, could be an effective strategy to sensitize difficult-to-treat AML patient subgroups, such as those with TP53 alterations, to the venetoclax/azacytidine combination
J., Forni, L

The sole isoform in rodents that encodes GDH is GLUD1 (Spanaki et al., 2010)

The active ingredient is identical, so the transition is straightforward

Substrate Specificity of the Ubiquitin and Ubl Proteases

To close the feedback loop when vitamin D and phosphorus levels decline, FGF23 is inhibited, leading to an increase in vitamin D levels (139, 141)