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"Guidelines for the diagnosis and treatment of cobalamin and folate disorders"
Phase IIb ran to 24 weeks without reported safety signals

doi: 10.1039/C5SM02710A
It causes oxidative stress

Ongoing signaling stops once you stop applying, which is why most users treat GHK-Cu as long-term maintenance

In isolated mitochondria, coenzyme Q 10 can protect membrane proteins and mitochondrial DNA from the oxidative damage that accompanies lipid peroxidation (5)
