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2123 In addition to enzymatic assays, biophysical methods including isothermal titration calorimetry, surface plasmon resonance, and the fluorescence polarization assay can measure direct interactions between NNMT and its substrates or inhibitors
Fosgonimeton failed its primary endpoint in three separate clinical trials: ACT-AD (Phase 2, mild-to-moderate Alzheimers disease, June 2022)
Loikas S, Koskinen, Irjala K, et al
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