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doi: 10.1186/s12870-024-05093-6 96 LouisN.DhankherO

Crossing these Jnk1 LoxP/LoxP / Jnk2 -/- mice with Alb-Cre mice produced Jnk hepa ( Jnk hepa mice developed higher liver injury than wild-type animals after APAP overdose, suggesting a beneficial role for combined Jnk1 and Jnk2 activation in hepatocytes during APAP-induced hepatotoxicity

The generation of cell lines was conducted under NMFS permit # 22479
Overexpression of insulin-like growth factor-1 induces hyperplasia, dermal abnormalities, and spontaneous tumor formation in transgenic mice

Furthermore, melatonin treatment has been shown to mitigate MTX toxicity, as evidenced by reduced homocysteine level (Chen et al

As expected, we found a significant inverse correlation between expression of Nrf2/Prdx6 and increased ROS levels during aging