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92,93 Other natural molecules Other natural molecules, such as fisetin, 94 myricetin, 95 theaflavin, 96 thearubigin, 96 trichostatin, 97 kazinol, 98 genistein, silibinin, luteolin, boswellic acid, mahanine and selenium, have been reported to exhibit a DNMT inhibitory effect, 99 which makes them good candidates for use as hypomethylating agents for CRC treatment (Table 2)

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PMC 4009342