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Their results revealed a dosedependent impact, with the 100 mg/kg BW group exhibiting significant ECG alterations, increased heart enzymes (creatine kinaseMB and lactate dehydrogenase), elevated oxidative stress markers (MDA and nitric oxide) and reduced GSH levels, accompanied by histopathological damage to cardiac tissues

In this study, we demonstrated that lactate facilitated lung metastasis by inducing and maintaining the stemness potentials of detached breast cancer cells

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Time injections strategically: - Post-workout: Consume 30-50g carbs immediately after training, inject, then eat full meal 30 min later - Before bed: Eat small meal with 20-30g slow-digesting carbs first 3

A number of signaling pathways, such as those involving p53, p21, phosphatidylinositide 3-kinase (PI3K), protein kinase B (PKB, also known as Akt), mammalian target of rapamycin (mTOR), NF-E2-related factor 2 (Nrf2), antioxidant responsive element (ARE), nuclear factor kappa-B (NF-B), Toll-like receptor 4 (TLR4), TLR2, NOD-like receptor thermal protein domain associated protein 3 (NLRP3)/Caspase-1, mitogen-activated protein kinases (MAPKs), and Wnt/-catenin pathways, were exemplified to participate in AFB1-induced toxic effects in in vitro and in vivo models [45,46,47,48,49,50]