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Studies have demonstrated that at single doses above 0.5 to 1 gram, the intestinal transporters reach their maximum capacity

Johnson EC, Carter EK, Dammer EB, Duong DM, Gerasimov ES, Liu Y, Liu J, Betarbet R, Ping L, Yin L, Serrano GE, Beach TG, Peng J, De Jager PL, Haroutunian V, Zhang B, Gaiteri C, Bennett DA, Gearing M, Wingo TS, Wingo AP, Lah JJ, Levey AI, Seyfried NT

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These two properties are thought to be the mechanisms behind L-arginine as an antifibrotic agent (25)

[DOI] [PubMed] [Google Scholar] 129.Dean O., Giorlando F., Berk M