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The two exposed faces of the pentamer are called the A face (or the effector face) and the B face (or the binding face), respectively

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Jacobsen G, Rasmussen K, Bregnhj A, Isaksson M, Diepgen TL, Carstensen O (2022) Causes of irritant contact dermatitis after occupational skin exposure: a systematic review

Melanotan 1 Highly selective for the MC1R receptor Produces more gradual and stable pigmentation effects among research models Has a narrower range of systemic effects when administered within research settings Melanotan 2 Broader receptor affinity as compared to Melanotan 1 Demonstrates faster pigmentation responses in animal models Broader receptor affinity could lead to a wider spectrum of possible adverse effects From a research viewpoint, Melanotan 1 is better characterized for photoprotection and pigmentation research studies

A 64-Year-Old Woman with Diabetes Mellitus Associated with Increased Urinary Oxalate Excretion Presenting with Acute Kidney Injury Due to Acute Oxalate Nephropathy