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The implication of GST polymorphisms may be significant as studies suggest that that loss of mu, pi and theta GST genes increase susceptibility to inflammatory diseases, and a genetic deficiency of GSTM1 is associated with increased susceptibility to ozone-related asthma [61] and to susceptibility to AFB1-mediated damage to human liver cells [62]

Carvalho , Mrcia Carvalho , Joao Mauricio Castaldelli-Maia , Giulio Castelpietra , Alberico L

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Therefore, Cu 2+ coordination by the histidine residues in PrP is central to either neuroprotection or neurodegeneration

NPs with diameters of 2050 nm can achieve efficient accumulation in the LNs, whereas large nanoparticles are easily captured by the reticuloendothelial system [225]

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