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Aggregation of alpha-synuclein in Lewy bodies of sporadic Parkinsons disease and dementia with lewy bodies

P., Ahuja, N., Toyota, M., Bronner, M

Iron has been shown to promote aggregation and pathogenicity of the characteristic aberrant proteins, -amyloid, tau, -synuclein, and TDP43, in these diseases

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The hypoxic microenvironment can inhibit lipoteichoic acid-mediated immune tolerance and prolong the survival of neutrophils