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While all studies adequately ascertained exposure and ensured comparability between outcome groups by controlling for confounders, 42% (n = 5) did not provide adequate sample representativeness and size, and 17% (n = 2) did not report the non-response rate

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Stanclift and Gilson [196], used prednisolone for tumor debulking and concluded that the adoption of 3 cm lateral surgical margins based on tumor size after neoadjuvant treatment were sufficient to obtain free margins

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