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However, sample sizes were modest, and long-term safety and efficacy data remain absent from peer-reviewed literature

Disclaimer: L-Theanine is a research compound not approved by the FDA

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Moreover, in France identified a link between bad nutrition and depression incidence, it was most likely due to reverse causation, with depression raising the likelihood of poor eating habits (246)

Murine studies published in Cell used 5mg/kg as a threshold dose for measurable senescent cell reduction in naturally aged mice, with 10mg/kg producing maximal effect without off-target toxicity