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doi: 10.1093/brain/awz024

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Definition Box Signal Peptide: A short peptide sequence that triggers downstream cellular responses (gene expression, enzyme activation, cytokine release) by interacting with receptors or transport proteins rather than by being incorporated into larger structures

This medication is taken once daily on an empty stomach, at least 30 minutes before the first food, beverage, or other oral medication of the day

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Knee Osteoarthritis Some Meniscus Tears Chondromalacia Patella (Runners Knee) Patellar Tendonitis Ligament Sprains or Tears (MCL, LCL, ACL) Hip Osteoarthritis Tendonitis SI Joint Dysfunction Trochanteric Bursitis Elbow Lateral Epicondylitis (Tennis Elbow) Medial Epicondylitis (Golfers Elbow) UCL Tears (in place of Tommy John surgery) Hand & Wrist Osteoarthritis Tendonitis DeQuervains Tenosynovitis Ankle & Foot Achilles Tendonitis or Partial Tears Osteoarthritis Plantar Fasciitis Ankle Sprains Ligament Injury Shoulder Osteoarthritis Rotator Cuff Tendonitis Tendonopathy Partial Tears Labral Tear Biceps Tendonitis Spine Facet Joint Arthropathy Sacroiliac (SI) Joint Dysfunction Disc Bulges & Tears Sciatica (lumbosacral radiculopathy) Yes