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Description
Elevated serine/threonine phosphorylation of IRS-1 and IRS-2 inhibits their binding to the juxtamembrane region of the insulin receptor and impairs their ability to undergo insulin-induced tyrosine phosphorylation
Hepokoski, M
Especially Whitney
Phase 2 trial in type 2 diabetes (Lancet 2023) showed similar additive benefit for the combination
The concentration of Cd in the livers of individuals who are not occupationally exposed grows steadily with age
298 Additionally, promoting mitophagy also helps mitigate the inflammatory response in aging
