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Description
The researchers found that 0404 operated through a positive feedback loop involving the p53/miR-34a/SIRT1 pathway to induce cell apoptosis at a nanomolar concentration

Modulates the Immune System: It can help bring overactive or underactive immune responses back toward balance supporting resilience and recovery

If this increase in GSH was blocked, liver regeneration was impaired (Huang et al., 2000a)
[DOI] [PubMed] [Google Scholar] Ghezzi P, Di Simplicio P

longum , S

Haematologica 89 (4): 427-34, 2004
