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Interestingly, our bodies also produce aldehydes as part of the neurotransmitter cycle- and aldehydes are toxic

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There was also an increase in GSH1 transcript level in the GSH-supplement condition, suggesting the possibility of pTEF1 regulation by relatively high ( 1 mM) extracellular GSH

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Advances in Glutathione Research for Disease Research Targeted therapy for GSH metabolism has become a research hotspot, and metabolomics and proteomics technologies have also provided powerful tools for GSH-related research: Targeting GSH metabolism : Inhibiting key molecules such as GCLC, xCT (cysteine uptake carrier) or SLC25A39 (mitochondrial GSH transporter), or using GSH-depleting nanozymes, has shown the potential to enhance ROS-mediated tumor cell death and improve related disease symptoms in preclinical models (such as cell models and animal models), providing new strategies for disease treatment