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Early support is critical - by the time symptoms appear, heart disease is often advanced

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Wang X, Luo H

By influencing tight junctions, endothelial cells, and microglial phagocytosis, astrocytes' TGF, IL10, and IL27 secretion can regulate immune cells' ability to cross the BBB [273]

They also demonstrated that dietary supplementation of apoE / mice with choline, TMAO or betaine drives atherosclerosis by upregulating the scavenger receptors CD36 and SR-A1 on macrophages, leading to increased cholesterol accumulation and formation of foam cells (Geng et al., 2018)

I 2 = 90%, P = 0.32
