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The neuroendocrine phenotype emerges at least in part through suppression of AR signaling as the latter increases the expression of the neuronal transcription factor BRN2 [28]

Also L-carnitine with antioxidant and antiapoptotic properties can decrease cryodamages to sperm mitochondrial DNA and membrane through reduction of ROS and increase of mitochondrial antioxidants

However, the intestinal microbiome is also involved in the human amino acid homeostasis, and vice versa amino acids have an impact on the abundance of the microbes that utilize them [14]

et al.: Mechanism of Prominent Trimethylamine Oxide (TMAO) Accumulation in Hemodialysis Patients

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Traina and colleagues suggest that ALC might rebalance the disorders underlying neuronal ceroid lipofuscinosis disease which are related to a disturbance in pH homeostasis