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By enhancing succinate dehydrogenase (Complex II) activity to promote oxidative phosphorylation and cooperatively suppressing HIF-1 and IL-1 expression, Arg2 precisely regulates the inflammation resolution process (150).In summary, macrophage metabolic reprogramming extends far beyond a simple switch in energy supply, representing instead a highly integrated and cross-pathway global regulatory network

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Corcho, I., Hernndez, F., Reyes, N., Carballo, A.L., Pea, O., Reyes, T., Yanes, L., Cambios del sistema inmune en procesos inflamatorios durante la aplicacin de la ozonoterapia, Rev