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The most severe potential adverse effect is seizure

Best Practices Rotate injection sites to avoid irritation Use insulin syringes (subcutaneous or intramuscular) Pair with nutrient timing include carbs + protein post-injection Avoid combining with fasted cardio or insulin-modulating agents Monitor energy, recovery, and blood sugar response Low-dose IGF-1 therapy shows beneficial effects on muscle recovery and composition without adverse metabolic effects when monitored appropriately. Juul, A

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Winkelmann, A., Loebermann, M., Reisinger, E

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Cancer Res 54 : 55315534 Karnieli E, Werner H, Rauscher II FJ, Benjamin LE, LeRoith D (1996) The IGF-I receptor gene promoter is a molecular target for the Ewing's sarcoma-Wilms' tumor 1 fusion protein