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CHAC2 itself is regulated both transcriptionally and post-translationally, with its degradation mediated by the ubiquitin-proteasome pathway ( In lung cancer, however, the CHAC2-mediated increase in ROS triggers the MAPK pathway

The dark side of foetal bovine serum in extracellular vesicle studies

Int J Mol Sci 20:6194

Glut9-mediated urate uptake is responsible for its protective effects on dopaminergic neurons in Parkinsons disease models

Signal transduction events triggered by adrenergic stimulation of BAT are effected via the activation of G s type G-proteins associated with the -adrenergic receptors

Functional ODC is a homodimer and requires pyridoxal phosphate (PLP), derived from vitamin B6, as a cofactor