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In addition to 5-amino-1MQ, JBSNF-000088 is another NNMT inhibitor that is promising for treatment of obesity and associated T2D

[DOI] [PMC free article] [PubMed] [Google Scholar] 11.Martinussen C, Bojsen-Moller KN, Svane MS, Dejgaard TF, Madsbad S

Reactions were performed with 2 M nicotinamide and 30 M phosphoribosyl pyrophosphate (PRPP) in the presence of 1mM ATP and recombinant human NAMPT enzyme

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doi: 10.2337/db10-0805