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Alcohol Consumption: A New Risk Factor for Arterial Stiffness
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An increase in heart rate of 10 beats/minute or greater or an increase in systolic blood pressure of 15 mm Hg or greater suggests an intravascular injection

2003, 121C: 38-52

Begin with the lowest effective dose and monitor digestion, sleep, and cardiovascular responses

(PubMed) effrey BG, Weisingerb HS, Neuringer M, Mitcheli DC
