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Ketamine, a dissociative anesthetic, works along the glutamate pathway and has shown promise as a potential treatment for severe depression in small doses.80 In nootropic supplements, caffeine, cocoa, theobromine, and L-theanine may influence glutamate
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These results suggest that the respective macrocycles probably bind different regions of the Met ectodomain, requiring an adequate length of cross-linker for their effective dimerization of Met
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