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Thus, the need for a therapy that can alleviate the social and economic burden that presents itself with debilitating and recurring soft tissue injuries is apparent

[DOI] [PubMed] [Google Scholar] 591.Maurer, M

A dysfunction in System Xc- results in reduced cysteine availability, which limits GSH synthesis, weakens antioxidant defenses, and increases susceptibility to lipid peroxidation, thereby accelerating ferroptosis (67)

In this work, we found that the restriction of the metabolism of cysteine ( cysB and cysE ) and inhibition of glutathione synthesis ( gshAB ) did not lead to the expected increase, but to a decrease in the sensitivity of the gmhA mutant to antibiotics, which is especially pronounced in the case of such a bactericidal antibiotic as nalidixic acid

Oral glutathione (pharmacokinetics and metabolism of orally administered glutathione): Oral glutathione is extracted from Torula yeast (Candida utilis)

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