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Jiean Huang, [email protected] These authors have contributed equally to this work Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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However, lactate promotes Treg stability and function

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The authors speculated that valproate reduced serum and liver carnitine concentrations, suppressing mitochondrial function, which in turn caused inhibition of the urea cycle [194]

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