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Cultures were subsequently cooled in an ice water bath for 15 min and centrifuged (4.000 g , 15 min, 4 C)

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GHK-Cu upregulates genes involved in collagen synthesis, extracellular matrix assembly, and tissue remodeling while downregulating genes associated with tissue destruction (matrix metalloproteinases, inflammatory cytokines)

According to Sabino Zani Jr, MD, a surgical oncologist who specializes in pancreatic cancer, minimally invasive surgery requires much smaller incisions and may speed recovery

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