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Fluorescent RGD-based pro-apoptotic peptide conjugates as mitochondria-targeting probes for enhanced anticancer activities

61 KutscheraM.EngstW.BlautM.BrauneA

Studies that investigate the potential of CJC-1295 apply 1000-2000 mcg per week, administered two to three times per week via subcutaneous injections

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These compounds activate HIF-1 and PI3K/Akt signaling, upregulating VEGF expression and enhancing nitric oxide (NO) production via eNOS phosphorylation