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(2011) characterized the in vitro potency of a variety of Mps toward inhibiting HO-1 and HO-2 isoenzymes, using rat and mouse spleen and brain tissue, respectively, as sources of the isoenzymes

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Besides, BSO involved in the depletion of GSH increases oxidative stress in the cells through increased sensitivity of the cells to H 2 O 2 and several other oxidative stress-inducing agents [27]

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The noradrenergic system, particularly through 2A -adrenergic receptor signaling, modulates executive function and emotional regulation